Provo.X – GANSHORN Medizin Electronic GmbH

The art of lung diagnostics.

We are a manufacturer of versatile PFT devices – with a focus on durability and simple design. With over 40 years of experience.

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Provocation system for safe and hygienic challenge testing

Perform inhalation provocation tests exceptionally fast and with reproducible results

GANSHORN’s Provo.X is an aerosol dosimeter that is able to do specific and unspecific provocations within seconds – no matter where the measurements are carried out.

Perform inhalational provocation tests quickly and with reproducible results. The PC based system is designed for accurate and safe direct challenge tests. Various protocols and sequences can be easily adapted. All accessories with patient contact are designed as disposable items, which 100 % excludes possible cross-contamination. Eliminating the disinfection steps save time and money.

Advantages

Provo.X in detail

Features

Powerful compressor

Optimal hygiene solution

The compressor with a three-liter compressed air tank guarantees stable nebulization pressure and low noise level (operating time of only about 3-5 minutes per week).

All components of Provo.X that can be contaminated are designed for single use and do not need to be sterilized. This saves time and makes the Provo.X the only device on the market with a perfect hygienic solution.

Threshold-controlled aerosol delivery

User-Friendly Software

Provo.X administers the aerosol dose in a breath-synchronous manner during the inspiration phase, ensuring that the aerosol reaches deeply into the airways. That improves the reproducibility of results .

GANSHORN´s software LFX includes pre-installed protocols, such as ATS and DGP, and allows for the creation and storage of custom protocols with up to 14 stages.

Measurement principle

An FVC test is typically used for reference and post-provocation assessment. Other possible
measurements for a provocation sequence include:
– Offline parameter (manual input)
– No measurement (e.g., biomarkers)
– Body plethysmography

Each control module allows for specific measurements and can be used to determine the PD reference with percentage differences from the base or pre-measurements.

The patient inhales an aerosolized provocation substance using a nebulizer, taking slow, deep breaths. The substance is nebulized during the inspiratory cycle for a set bolus time. If inhalation is shorter than bolus time, the remaining time is added to the next breath. LFX monitors breathing and administers the aerosol only during inhalation, optimizing delivery and minimizing waste. The total dose per stage is automatically adjusted for short breathing cycles. As nebulization progresses, water vapor increases the concentration of the test substance, so the volume of the nebulizer solution should be increased accordingly.

After a set residence time (1-20 min), indicated
by a countdown, the user undergoes a body
plethysmography, spirometry or oscillometry
test. Then, the next provocation stage can
begin. This cycle of inhalation and control tests
repeats until all stages are completed or the
patient opts to stop.
For each control module, measurements can be
defined and used for the PD reference with
percentage differences from the base, such as
a 20% decrease in FEV1 or a 100% increase in
sRaw.

If after the last inhalation the FEV1 or alternative control parameter doesn’t fall below the threshold, the provocation test is regarded negative and asthma can be ruled out. If the threshold (PD20 in spirometry) is reached, the provocation should be stopped and the PD20 value of this positive provocation test is reported.

Set-Ups

with SpiroScout or PowerCube Spiro+

combination with
desktop spirometer

with PowerCube Diffusion+

combined with diffusion system

Stand alone device

with support arm and clamp for flexible mounting

in PowerCube Body+

for integrated use in
body box

Software platform

The LFX software is the GANSHORN user-friendly interface, developed with the physiologist in mind. It provides all tools necessary to perform every task done in the laboratory, while remaining easy to operate. Built on state-of-the-art Windows tools like .Net, C# and SQL database, the software is the future of modern respiratory diagnostics. LFX has built-in quality control monitoring based on ATS/ERS guidelines, which are accessible during and after the measurements are performed.

Additional downloads

Technical data sheet

PDF, English

Product brochure

PDF, English

Instruction manual

PDF, English

GANSHORN reserves the right to make changes in design, specifications and features shown, or discontinue the product described at any time without notice or obligation. Images may be representative. Device availability in your market is subject to regulatory approval.